Research Scientist, Immunology

The Impact You’ll Make

We are seeking an innovative Research Scientist to join our Experimental Immunology team at our new state of the art laboratories in Oxford. In this primarily lab-based role, you will provide critical cellular data to support therapeutic projects, often venturing into areas of novel biology. You will work within the Recursion Discovery team to uncover solutions for a variety of target classes and I&I indications.

You will have the freedom to design, plan, and execute complex experiments and help drive projects from target ideation through validation and into adoption in the portfolio. You will develop translationally relevant screening assays and function as an immunology expert within project teams. This role offers substantial scope for continuous learning, with exposure to all stages and disciplines of the drug discovery process. You will also have the opportunity to present your findings both internally and externally and will have access to state-of-the-art assay technologies (FRET, Luminescence, FACS, High-Content Imaging) and advanced automation and will be encouraged to evaluate and deploy the latest scientific developments to create efficient processes

In this role, you will:

• Design and execute complex in vitro assays using primary human immune cells and patient-derived tissues for use in target validation, mechanism of action studies and small molecule screening.
• Working closely with team leads to actively contribute to projects through the entire development lifecycle by supporting the transition from initial target ideation to advancing in the pipeline
• Deploy state-of-the-art technologies such as flow cytometry and high-content imaging to address key scientific questions.
• Advance early drug discovery programs by incorporating the latest scientific developments into workflows and by working closely with external collaborators to ensure generation and delivery of critical data
• Provide immunology expertise to guide in vitro and in vivo workstreams in cross functional matrix project teams

The Team You’ll Join

You will be joining an established immunology group consisting of several experienced immunologists working across a number of indication spaces. The experimental immunology team work on a wide range of projects spanning target ideation through to advanced preclinical programs. You will work within project strategy and execution set by project leaders, and collaborate extensively with data scientists, chemists, and biologists throughout the organization and externally, to advance milestones and provide insights to further advance Recursion’s capabilities.

The Experience You’ll Need

• Ph.D in Immunology or a related discipline or a BSc/MSc degree with significant relevant experience, preferably in the pharmaceutical or biotechnology industry
• Extensive hands-on experience in designing, executing and optimizing in vitro assays utilizing primary human immune cells/patient derived tissue
• In depth understanding of gut, skin or airway inflammation and knowledge of in vitro relevant translational models
• Experience of screening small molecules and working on a drug discovery program and in-depth knowledge of data analysis including dose response relationships
• Exposure to a wide range of assay technologies such as ELISA, FRET, RT-PCR, flow cytometry and imaging with experience in target validation studies
• Excellent interpersonal and communication skills, both written and verbal, with ability to communicate technical information to a non-specialist audience while working across multiple projects

Working Location & Compensation:

This is a lab-based role in our Milton Park site. Employees are expected to work on-site 100% of the time, with occasional flexibility.

At Recursion, we believe that every employee should be compensated fairly. Based on the skill and level of experience required for this role, the estimated current annual base range for this role is £52,000 to £70,400. You will also be eligible for an annual bonus and equity compensation, as well as a comprehensive benefits package.

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